CTU Bern

Projects

Only major projects listed

Project Nr. Name
Start year
End year
One-Sentence Summary
Involved divisions Sponsor Funding
1366
SOLIDARITY TRIAL
2020
An international randomised trail of additional treatments for COVID-19 in hospitalised patients who are all receiving the local standard of care.
Study Website
Statistics
Central Data Monitoring
National Ministry of Health and the World Health Organisation
WHO
1338
PHARAO
2020
PHysiology in Anaesthesia Regarding Apnoeic Oxygenation during nasal cannula therapy at different flow rates. Comparing high flow, medium flow and low flow nasal cannula therapy. A single-centre prospective randomized controlled trial.
Statistics
Prof. Dr. med. Robert Greif
Departmental Anaesthesia Research Fund
1315
AB-PSP-001
2020
A multicenter, device clinical study for the early diagnostic os sepsis and potential impact on antibiotic management based on serial Pancreatic Stone Protein (PSP) measured using the abioSCOPE in critically ill patients at high risk of sepsis.
Statistics
ABIONIC SA
ABIONIC SA
1310
SARSCoV-2 and liver transplant
2020
Severe acute respiratory syndrome coronavirus 2 (SARSCoV-2) infection: epidemiology of an international liver transplant cohort.
Data Management Full Service
Prof. Dr. Jean-François Dufour
1309
CORON-ACT
2020
A multicenter, double-blind, randomized, controlled phase II trial on the efficacy and safety of tocilizumab in the treatment of coronavirus induced disease (COVID-19)
Data Management Full Service
Central Data Monitoring
Regulatory Support
Project Management
Statistics
Document Development
Prof. Dr. med. Peter M. Villiger
University Hospital Bern (Inselspital) and Roche Pharma (Schweiz) AG
1297
NIBED
2020
A randomized, controlled cross-over first-in-man safety and efficacy trial of a novel non-invasive bladder emptying device.
Document Development
Statistics
On-site Monitoring
Regulatory Support
Prof. Dr. Fiona Burkhard
Innosuisse Grant
1287
Laser treatment in vulvar Lichen sclerosus
2020
Effect of Treatment with the ablative fractional carbodioxide laser in vulvar Lichen sclerosus.
Data Management Full Service
On-site Monitoring
Prof. Dr. med. Michael D. Mueller
University Hospital Bern (Inselspital)
1276
HEADWIND II
2020
A non-randomised, controlled, interventional single-centre study for the design and evaluation of an in-vehicle hypoglycaemia warning system in diabetes.
Data Management Light Service
On-site Monitoring
Prof. Dr. med. Christoph Stettler
SNF
1243
Tissue graft versus collagen matrix in the treatment of gingival recessions
2020
A comparative assessment of connective tissue graft vs. a new collagen matrix for periodontal tissue thickening and coverage of single or multiple adjacent gingival recessions in the mandible of orthodontically treated patients. A single center randomized clinical trial.
Monitoring
Prof. Anton Sculean
Universität Bern Zahnmedizinische Kliniken
1222
Nicotine PKPD
2019
  Randomized crossover study comparing the pharmacokinetics and pharmacodynamics of two differet nicotine salt concentration vape system pods and an electronic cigarette using free-base nicotine
Data Management
Monitoring
Clinical Investigation
Dr. med. Evangelia Liakoni
Universitätsklinik für Allgemeine Innere Medizin
1206
S Napoli
2019   Survey on Salmonella Napoli
Data Management
Bundesamt für Gesundheit BAG BAG
1195
ESG
2019 Effects of Endoscopic sleeve gastroplasty on hormonal markers of glucose-homeostasis.
Data Management
PD Dr. med. Markus Laimer Scherbarth Stiftung
1123
VitCTrial 2019   Can Vitamin C reduce the risk of postoperative shoulder stiffness? A mono-center, double-blinded, randomized and placebo-controlled study.
Document Development
Regulatory Support
Data Management
Monitoring
Janine Antonov
Campus SLB Sonnenhof AG
1109
SAFE SSPE
2019   Clinical Surveillance vs. Anticoagulation for low-risk Patients with Isolated Subsegmental Pulmonary Embolism: A Multicenter Randomized Placebo-Controlled Non-Inferiority Trial.

 

Data Management
Statistics
Monitoring
Central Data Monitoring
Prof. Dr. med. Drahomir Aujesky
SNF
1107
DapaStudy 2019   SGLT-2 inhibition using Dapagliflozin during and after physical exercise – Effects on glycemic variability, hormonal regulators of glucose homeostasis and ketone body in type 1 diabetes a randomized, placebo-controlled, open-label, cross-over intervention study.
Data Management
Monitoring
Prof. Dr. med. Markus Laimer
SNF
1106
SM-FES 2019   Self-modulated functional electrical stimulation in Chronic Stroke Patients with Severe and Moderate Upper Limb Paresis: A Multi-Centre, Single-Blind, Randomized Parallel Study
Data Management
Statistics
Monitoring
Prof. Dr. Mauricio Reyes
Innosuisse
Intento SA
1096
VANCO 2019   Suprafascial vancomycin powder for prevention of surgical site infections after instrumented posterior spinal fusion: A randomized controlled trail.
Data Management
Monitoring
Dr. med. Christian Ulrich

Gottfried and Julia Bangerter & Rhyner Stiftung

1083
HDMM 2019   HDM201 and midostaurin (HDMM) in relapsed/refractory AML with FLT3mut and TP53wt and in newly diagnosed AML with FLT3mut and TP53wt not fit for intensive chemotherapy; a phase I study.
Data Management
Monitoring
Prof. Dr. med. Thomas Pabst
Novartis
1073
PedIndex 2019   Comparing intranasal dexmedetomidine with oral or rectal midazolam for procedural sedation in the pediatric emergency department: a monocenter, prospective, randomized, rater-blinded study at the Pediatric Emergency Department Bern
Data management
Monitoring
Dr. med. Julia Höffe
Stiftung Batzebär
1061
EpiOs 2019   Early feasibility study on EpiOs (Epi means around, Os means bone) leads.
Data Management
Monitoring
Wyss Center for Bio and Neuro Engineering
Wyss Center
1059
HemMa SCD
2019   A Prospective Cross-Sectional Observational Study to Identify and Characterize Hematological Markers and Predictors of Hemolysis Severity of Sickle Cell Disease in Patients with Type Hemoglobin SS and S/ß-thal and to evaluate differences compared to a control group without hemolysis.
Document Development
Regulatory Support
Data Management
Statistics
Monitoring
PD Dr. med. Alicia Rovó
CSL Behring AG
1058
SRT Phase I
2019
  Quantitative and qualitative evaluation of selective retina therapy (SRT) in combination with real-time optical coherence tomography (OCT) for laser dosimetry
Document Development
Regulatory Support
Data Management
Monitoring
Central Data Monitoring
Prof. Dr.-Ing. Dr. med. Sebastian Wolf
Universitätsklinik für Augenheilkunde, Inselspital Bern
1052
Proaktiv 2019
  A cluster randomized controlled trial of palliative needs assessment and palliative care in general practice.
Data Management
Statistics
Prof. Dr. med. Steffen Eychmüller
SNF
0917
B&B VTablation 2020
Prospective Registry of Patients Undergoing Ventricular Arrhytmia Catheter Ablation at the University Hospitals Bern and Basel.
Data Management (outsourced)
Central Data Monitoring
Prof. Tobias Reichlin
Department of Cardiology at University Hospital Bern
0909
PSP Diagnosis of Sepsis
2019   Prognostic Value of Pancreatic Stone Protein in Adult Patient: Systemic Review and Metaanalysis
(MetaPSP)
Statistics
Prof. Dr. med. Yok-Ai Que

Abionic
0906
PAPA ARTiS
2019   Paraplegia Prevention in Aortic Aneurysm Repair by Thoracoabdominal Staging with ´Minimally-Invasive Staged Segmental Artery Coil-Embolization`: A Randomized Controlled Multicentre Trial.
Monitoring Prof. Dr. med. Jürg Schmidli
German Research Foundation
European Union´s Horizon 2020
0881
GCA Registry
2019   An open-ended registry of patients with giant cell arteritis.
Data Management
Statistics
Prof. Dr. med. Peter M. Villiger
 
0883
Bone Anchored Port
2019   Metaanalysis for the historical control of the Bone Anchored Port - a Novel Vascular Access for Hemodialysis Treatment
Statistics Thomas Frei
Diavantis AG
0877
PPVRP 2019   The Influence of a Pre-Operative Preparatory Virtual Reality Program on the Self-Assessed Anxiety of Children Undergoing Elective Surgery.
A Randomized Controlled Trial.
Data Management
Prof. Dr. med. Steffen Berger
Department of Pediatric Surgery, Inselspital University Hospital
0866
OPTICO LM
2019   Multimodality assessment of intermediate left main stenosis: Comparison of optical coherence tomography-derived minimal lumen area, invasive fractional flow reserve and FFRCT
Data Management
Statistics
Monitoring
Prof. Dr. Lorenz Räber
Abbott
Heartflow
0856
EMISI Trial 2019   Efficacy of Metamizole versus Ibuprofen and a Short Educational Intervention versus Standard Care for patient with Acute and Subacute Low Back Pain: A Randomized, Factorial Trial. Methodology
Data management
Monitoring
Reporting
Dr. med. Maria Wertli
SNF
0829
CONNECT 2019   A Randomized Comparison of Long-Term Vascular Healing between Biodegradable Polymer (BP) versus Durable Polymer (DP) Everolimus Eluting Stents in Acute ST-Elevation Myocardial Infarction. Statistics Prof. Dr. Lorenz Räber
Boston Scientific
0746
ESTxENDS 2018 Efficacy, Safety and Toxicology of Electronic Nicotine Delivery Systems as an aid for smoking cessation: The ESTxENS multicentre randomized controlled trial Data Mangement
Statistics
Monitoring
Central Data Monitoring
Prof. Dr. Reto Auer
SNF
Lungen Liga Bern
Swiss Cancer League
Tobacco Prevention Fund TPF
0158
CLEVER-ACS 2019   A phase II randomized double-blind multi-centre placebo-controlled trial on the effects of a short course of everolimus in patients with acute ST-Elevation Myocardial Infarction on infarct size, left ventricular remodelling and inflammation.  Data Management
Statistics
Prof. Dr. med. Frank Ruschitzka SNF
0741
BISS
2017
  A multi-center, randomized, 18-month, non-inferiority study to compare the efficacy of botulinum toxin versus conventional strabismus surgery in the treatment of secondary strabismus, in patients aged between 1 and 17 years.
Data Management
Statistics
Monitoring
Project Management
Central Data Monitoring
PD Dr. med. Mathias Abegg
SNF
0701
SWIFTdirect 2017   Solitaire™ With the Intention For Thrombectomy Plus Intravenous t-PA Versus DIRECT Solitaire™ Stent-retriever Thrombectomy in Acute Anterior Circulation Stroke
(SWIFT DIRECT)
Data management     
Central data monitoring         
Monitoring        
Statistics
Prof. Dr. Urs Fischer Medtronic Minneapolis, Minnesota, USA
0689
H-PACS 2016   Prophylactic mesh implantation in patients requiring emergency laparotomy for the prevention of incisional hernia: A randomized controlled trial. Data Management
Monitoring
Statistic
Prof. Dr. med. Guido Beldi Lifecell
0679
ELAN 2017   An international, multicenter randomized-controlled trial comparing early versus standard initiation of anticoagulation in patients with stroke and atrial fibrillation. Data management     
Central data monitoring         
Monitoring        
Statistics
Prof. Dr. med. Urs Fischer SNF
0677
Simpl'HIV trial 2017   Evaluation of a simplified strategy for the long-term management of HIV infection: a non-inferiority, randomized, controlled, open-label clinical trial. Data Management
Monitoring
Statistic
Prof. Dr. med. Alexandra Calmy SNF
0670
DAWN2 CH 2016   Diabetes Attitudes Wishes and Needs (DAWN)2 Study in Switzerland: A survey study of psychosocial issues in diabetes and patient-centered diabetes care. Data Management
PD Dr. med. Markus Laimer Novo Nordisk AG
0645
EVOPACS 2017   Effect of PCSK9 inhibitor with EVOlocumab on early reduction of LDL-cholesterol levels in patients with Acute Coronary Syndromes (EVOPACS)- a randomized, double-blind, placebo-controlled multicenter study. Project Management       
Data management     
Central Data Monitoring         
Monitoring        
Statistics
Prof. Dr. Stephan Windecker Amgen Switzerland AG
0640
NOSTONE 2016   A 3 year prospective, multicenter, double blind, placebo-controlled trial to assess the effectiveness of standard and low dose hydrochlorothiazide treatment in the recurrence prevention of calcium containing kidney stones. Methodology
Project Management
Data Management
Monitoring
Central Data Monitoring
Statistics
Prof. Dr. med. Daniel Fuster SNF
0636
SERVE 2017   Effect of phosphodiesterase-5 inhibition with Tadalafil on SystEmic Right VEntricular function – a multi-center, double blind, randomized, placebo-controlled clinical trial – SERVE Trial. Methodology
Data Management
Monitoring
Statistics
Reporting
Prof. Dr. Markus Schwerzmann SNF
0628
SCOPE I 2017   A randomized controlled non-inferiority trial evaluating early safety and clinical efficacy of the Symetis ACURATE Neo compared to the Edwards Sapien 3 bioprosthesis in transcatheter aortic valve implantation. Data Management
Statistic
Monitoring
Reporting
Prof. Dr. Stephan Windecker Symetis SA
0634
MASTER DAPT 2016   Management of high bleeding risk patients post bioresorbable polymer STEnt implantation with an abbReviated versus prolonged DAPT regimen: an international, multicenter, randomized-controlled trial. Data Management
Monitoring
Statistic
Reporting
European Cardiovascular Research Institute (ECRI) Terumo Medical Corporation
0632
SYMPTOM NAVI Pilot 2016   Implementation of the Symptom Navi© Program for cancer patients in ambulatory services: A cluster-randomized pilot study. Data Management
Monitoring
Statistic
Dr. Manuela Eicher Stiftung Lindenhof Bern
0613
SCRIPT 2016   A randomized-controlled trial evaluating the effects of regulated cannabis selling in pharmacies - The Safer Cannabis - Research In Pharmacies Trial. Project Management
Data Management
Statistics
Dr. med. Sven Trelle University of Bern
0606
REVEAL in TAVI 2016   Prospective research project investigating the incidence of arrhythmias in patients undergoing transcatheter aortic valve implantation. Data Management Prof. Dr. med. Laurent Roten SNF
Medtronic (Schweiz) AG
0536
SAAL 2015   CD34+  selected versus unselected  autologous stem cell transplantation in advanced stage mantle cell and diffuse large B-cell  lymphoma patients, a randomized phase II study (the SAAL-trial). Data Management
Monitoring
Statistics

 

Prof. Pabst Thomas  

Miltenyi Biotec GmbH

0533
OPTICO BVS

2016

 

A randomized-controlled trial to compare optical-coherence-tomography- with angiography-guided percutaneous coronary intervention in patients with de-novo coronary artery disease undergoing coronary revascularization.

Methodology
Project Management
Data management
Monitoring
Statistics
Reporting

 

Dr. Räber Lorenz St. Jude Medical
0524
Effect of anaesthetic techniques on clinical outcome after LSP, RA vs GA, a prospective RCT 2016   A randomized-controlled trial to evaluate the effect of general versus regional anesthesia on clinical outcomes in patients undergoing lumbar spine surgery. Data Management
Statistics

 

MD Bänziger Bertram  
0468
OSCAR GALILEO 2015   A global multicenter, open-label, randomized, event-driven, active-controlled study comparing a rivaroxaban-based antithrombotic strategy to an antiplatelet-based strategy after transcatheter aortic valve replacement (TAVR) to optimize clinical outcomes. Monitoring Cardialysis BV Bayer AG
0465
Ebola vaccine trial 2015   Two trials of a new Ebola Virus vaccine: 1) ring-vaccination (cluster-) randomized-controlled trial to assess the efficacy of a single intramuscular dose of a vesicular stomatitis virus-based vaccine against Ebola virus disease (rVSV-ZEBOV) and 2) a single-arm phase II trial in front-line workers to determine the safety and activity of rVSV-ZEBOV. Project Management

Henao-Restrepo Ana Maria

 
0458
BIOSTEMI
2016   A randomized-controlled trial of a sirolimus-eluting stent with an ultrathin strut biodegradable polymer (Orsiro) versus an everolimus-eluting stent with a durable polymer (XIENCE PRIME) in patients with acute ST‐segment elevation myocardial infarction undergoing primary percutaneous coronary intervention. Methodology
Project
Management
Data management
Monitoring
Statistics
Reporting
Prof. Dr. med. Pilgrim Thomas Biotronik AG
0453
TOLERANT 2015  

A randomized, controlled trial investigating the efficacy and safety of two different aflibercept treatment regimens (strict vs. relaxed) in patients with exudative age-related macular degeneration (AMD).

Methodology
Project Management
Data management
Monitoring
Statistics
Reporting


Prof. Dr. Dr. med. Wolf Sebastian Bayer (Schweiz) AG
0449
DECO-SSI  2015   A randomized-controlled trial evaluating the effect preoperative Staphylococcus aureus decolonization on surgical site infections in patients undergoing elective orthopedic surgery. Methodology
Data management
Monitoring
Statistics

 

Dr. med. Brügger Jan The Lindenhof Fund for Teaching and Research, Bern  
0441
MDS Registry 2014   A multicenter observational, retro- and prospective, longitudinal study of patients with suspected or confirmed myelodysplastic syndrome (MDS), myelodysplastic/myeloproliferative neoplasia (MDS/MPN), or acute myeloid.

Data Management

Dr. med. Bonadies Nicolas  

Novartis Pharma Schweiz AGCelgene GmbH

 

0428
BEB 2015   A randomized phase II trial comparing BeEAM with BEAM as conditioning regimen for autologous stem cell transplantation (ASCT) in lymphoma patients (BEB-trial). Monitoring

Prof. Dr. med. Pabst Thomas

EMPIRIS
Mundipharma Medical Company
0415
OPERAM 2016   A cluster-randomized trial evaluating whether structured drug review with appropriateness assessment (supported by a dedicated decision aid i.e. software) reduces the rate of drug-related hospital admissions in multimorbid patients with polypharmacy as compared to standard of care. Methodology
Project Management
Data management
Monitoring
Statistics
Clinical investigation
Laboratory
Reporting

 

Prof. Dr. med. Nicolas Rodondi EU HORIZON2020
0337
MATRIX 2015   Minimising Adverse haemorrhagic events by TRansradial access site and systematic Implementation of angioX (MATRIX) Trial. Statistics Prof. Dr. Marco Valgimigli Medicines Company
Terumo
0333
SWITCH 2015   Swiss trial of decompressive craniectomy versus best medical treatment of spontaneous supratentorial intracerebral hemorrhage (SWITCH): a randomized controlled trial Data management
Central data monitoring
Monitoring
Statistics
Prof. Dr. med. Urs Fischer
Prof. Dr. med. Jürgen Beck
SNF
Schweizerische Herzstiftung
Inselspital
0228
SENStrial 2012   A structured early palliative care intervention for patients with advanced cancer – a randomized controlled trial with a nested qualitative study Project management       
Data management           
Monitoring        
Statistics
Clinical Investigation
Reporting
Prof. Dr. med. Steffen Eychmüller
SNF
0182
BAG_HFV-Pilot 2012   A randomized-controlled trial with a method-comparison study nested in each arm to assess how accurately and consistently clinical trials are categorized using two different approaches: an approach using criteria set forth in the Swiss Human Research Act which was enacted after this trial or an intuitive, ad-hoc approach. Methodology
Project Management
Data Management
Statistics
Reporting
Bundesamt für Gesundheit BAG  
0154
SAG TCCS 2012 A prospective Cohort study to determine the diagnostic performance and the clinical impact of a variety of tests, including conventional radiographs, computer tomographies (CT), serum tumour markers (AFP and beta-HCG) and clinical signs and symptoms aimed at early detection of relapse after curative therapy with documented complete remission. Data Management
Statistics
Central Data Monitoring
Monitoring
Dr. Christian Rothermundt
Kantonsspital St. Gallen
Swisscancer Anna Lisa Stiftung
Ostschweizer Stiftung für Klinische Krebsforschung OSKK
0104
GCA Tocilizumab Rheumatology 2013   A phase II, randomized, double-blind, placebo controlled strudy of Tocilizumab in patients with Giant Cell Arteritis Data management
Monitoring
Statistics
Reporting
Prof. Dr. med. Peter M. Villiger Roche Pharma (Switzerland) Ltd
0094
Bioscience Orsiro 2013   A Randomized Comparison of a Sirolimus-eluting Stent with a Biodegradable Polymer versus an Everolimus-eluting Stent with a Durable Polymer for Percutaneous Coronary Revascularization Monitoring Prof. Dr. Stephan Windecker BIOTRONIK
0093
Bioflow II 2012   Orsiro vs Xience stents with IVUS and OCT imaging substudies Statistics Prof. Dr. Stephan Windecker BIOTRONIK 
0087
PC Trial
2012   Randomized clinical trial comparing the efficacy of percutaneous closure of  patent foramen ovale (PFO) with medical treatment in patients with cryptogenic embolism Data management
Statistics
Foundation for Cardiovascular Research Abbott
Cordis
Medtronic 
0079
Global LEADERS 2013   Randomised trial to compare two dual-antiplatelet regimens in all-comers cardiovascular patients Methodology
Statistics
European Cardiovascular Research Institute (ECRI) Biosensors (Morges, Switzerland), AstraZeneca
0078
SPIRIT (10.10.CLI) 2012   A randomized-controlled trial comparing enteral feeding using standard nutrition with a new formula (Nestlé) in ICU patients. Methodology      
Data management            
Monitoring        
Statistics
Reporting
Maryam Olesen Nestlé Healthscience
0077
ETRELKA 2012   Effects of transcutaneous electrical stimulation (TENS) on knee pain and joint function in people with knee osteoarthritis: ETRELKA Methodology
Project Management       
Data management            
Monitoring        
Statistics
Clinical Investigation
Reporting
PD Prof. Dr. med. Stephan Reichenbach ARCO Foundation
0074
Swiss TAVI Registry
2011   Patient Registry Cardiology: To assess the periprocedural, in hospital, 30 day, and one year clinical outcome of patients undergoing transcatheter aortic valve implantation (TAVI) in Switzerland. Data management
Central data monitoring
Statistics
Prof. Dr. Peter M. Wenaweser Edwards
Medtronic
0052
HWI 2012 2017 A randomized, double blind trial to compare symptomatic therapy of uncomplicated lower urinary tract infections to antibiotic treatment, both in the ambulatory setting. Methodology
Project management      
Data management             
Monitoring       
Statistics
Clinical Investigation
Reporting
PD Dr. med. Andreas Kronenberg 
Swiss National Foundation
Swiss Academy of Medical Sciences
SwissLife foundation
Else Kroener-Fresenius foundation
0033
Lichen 2011 2014 Effectiveness of a topical progesterone therapy compared to conventional therapy with clobetasol propionate in patients with vulgar lichen sclerosus. A double-blind randomized phase II pilot study. Methodology
Project management      
Data management             
Monitoring       
Statistics
Reporting
Prof. Dr. med.
Andreas Günthert
SNF
0031
TTP Register
2012   An open ended registry of thrombotic thrombocytopenic purpura. Monitoring
Statistics
Prof. Dr. med. Johanna A. Kremer Hovinga SNF
Mach-Gaensslen Foundation
Baxter Innovations GmbH
0029
COMFORTABLE-AMI 2009   A randomized-controlled trial comparing a stent eluting biolimus from an erodable coating with a bare-metal stent in patients with acute ST-elevation myocardial infarction. Methodology      
Data management            
Monitoring        
Statistics
Reporting
Prof. Dr. Stephan Windecker SNF
Biosensors
0028
SWITCO65+ 2009 2013 A multicenter, interdisciplinary prospective cohort study to determine the predictors of clinically relevant medical outcomes, health-related quality of life, and costs of care among elderly patients with venous thromboembolism. Methodology
Project management       
Data management            
Monitoring        
Statistics
Laboratory
Reporting
Prof. Dr. med. Drahomir Aujesky SNF
0022
Titan-Endeavor RCT
2007 2013 The study sought to compare the efficacy of passive stent coating with titanium-nitride-oxide (TiNO) with drug-eluting stents releasing zotarolimus (ZES). Methodology
Data management
Statistics
Prof. Dr. Stephan Windecker Insel Foundation
0019
LEADERS 2006   Long-term clinical outcomes of biodegradable polymer biolimus-eluting stents versus durable polymer sirolimus-eluting stents in patients with coronary artery disease (LEADERS): 5  year follow-up of a randomised non-inferiority trial Statistics Prof. Dr. Stephan Windecker Biosensors Europe SA
0016
HVI_Tanzania 2012   A randomized-controlled trial testing the effects of presumptive antihelminthic treatment on progression of HIV in antiretroviral-therapy-naïve HIV-positive patients in a rural African setting with presumed high prevalence of Helminth infections. Methodology
Project management
Statistics
Reporting
Prof. Dr. Christoph Hatz  
0007
TFA 2009 2013 The aim of the study is to compare a diet rich in trans fatty acids (TFA) from ruminant sources with a diet rich in TFA from hydrogenated vegetable oils (PHVO) in regard to their effects on cardiovascular risk markers. Methodology
Data management
Statistics
Clinical Investigation
Prof. Dr. med. Dr. hc Hugo Saner Agroscope
0006
POC_OP 2012   A randomized-controlled trial to determine whether point-of-care coagulation testing of prothrombin time reduces the administration of fresh frozen plasma in patients undergoing major surgery and with intraoperative blood loss of more than 20% of their normal blood volume. Data management            
Statistics
PD Dr. med. Natalie Urwyler