CTU Bern (Clinical Trials Unit)

SWITCO 65+

SWITCO 65+ was a prospective cohort study funded by the Swiss National Science Foundation (grant FN 33CSCO-122659). CTU Bern has been responsible for the data management and statistical analyses.

SWITCO 65+ was a prospective cohort study conducted in nine Swiss study centers. More than 1,000 in- and outpatients aged ≥65 years with acute venous thromboembolism were recruited between 2009 and 2012. Patients were followed up for 2 years. Data collection included data on health-care utilization, quality of life, and clinical outcomes. A large biobank was also part of the study. The cohort is a unique opportunity to study short- and long-term outcomes in elderly patients with venous thromboembolism.

Services

Data management

CTU Bern was responsible to coordinate the set-up of the electronic data capturing system. The system integrated the clinical study database and the data management system of the biobank.

Statistical analysis

All main analyses have been done at CTU Bern.

Selected publications

Tritschler T et al. Predicting recurrence after unprovoked venous thromboembolism: prospective validation of the updated Vienna Prediction Model. Blood 2015; 126: 1949-51. doi: 10.1182/blood-2015-04-641225.

Méan M et al. The Swiss cohort of elderly patients with venous thromboembolism (SWITCO65+): rationale and methodology. J Thromb Thrombolysis 2013; 36: 475-83. doi: 10.1007/s11239-013-0875-2.